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DSM 74
CAS No. 898743-92-5
DSM 74 ( DSM74 )
Catalog No. M16464 CAS No. 898743-92-5
A potent, orally active PfDHODH inhibitor (IC50=0.3 uM) with antimalarial activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameDSM 74
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, orally active PfDHODH inhibitor (IC50=0.3 uM) with antimalarial activity.
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DescriptionA potent, orally active PfDHODH inhibitor (IC50=0.3 uM) with antimalarial activity; shows good plasma exposure in mice and is equally potent against PfDHODH and PbDHODH; suppresses growth of P. berghei in mice after oral administration.
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SynonymsDSM74
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorAntibacterial
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Research Area——
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Indication——
Chemical Information
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CAS Number898743-92-5
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Formula Weight293.25
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Molecular FormulaC13H10F3N5
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Purity>98% (HPLC)
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Solubility——
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SMILESFC(C1=CC=C(NC2=CC(C)=NC3=NC=NN23)C=C1)(F)F
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Chemical Name5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lukens AK, e tal. Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):799-804.
2. Gujjar R, et al. J Med Chem. 2009 Apr 9;52(7):1864-72.
3. Lee JJ, et al. urr Microbiol. 2014 Sep;69(3):286-91.
2. Gujjar R, et al. J Med Chem. 2009 Apr 9;52(7):1864-72.
3. Lee JJ, et al. urr Microbiol. 2014 Sep;69(3):286-91.
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DSM 74
A potent, orally active PfDHODH inhibitor (IC50=0.3 uM) with antimalarial activity.
